By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
MadisonyMadisony
Notification Show More
Font ResizerAa
  • Home
  • National & World
  • Politics
  • Investigative Reports
  • Education
  • Health
  • Entertainment
  • Technology
  • Sports
  • Money
  • Pets & Animals
Reading: 2025 NFL, CFB Odds: Greatest Bets for Giants-Commanders, Illinois-Duke
Share
Font ResizerAa
MadisonyMadisony
Search
  • Home
  • National & World
  • Politics
  • Investigative Reports
  • Education
  • Health
  • Entertainment
  • Technology
  • Sports
  • Money
  • Pets & Animals
Have an existing account? Sign In
Follow US
2025 © Madisony.com. All Rights Reserved.
Sports

2025 NFL, CFB Odds: Greatest Bets for Giants-Commanders, Illinois-Duke

Madisony
Last updated: September 5, 2025 4:23 pm
Madisony
Share
2025 NFL, CFB Odds: Greatest Bets for Giants-Commanders, Illinois-Duke
SHARE


Sam Panayotovich

FOX Sports Betting Analyst

Say football three times fast.

Now you’re ready for the weekend.

Not only do we have another full Saturday slate of college pigskin, the first NFL Sunday of the season is here, too. 

Last weekend’s picks went 1-2, and I’m still not sure how Cal freshman quarterback Jaron-Keawe Sagapolutele balled out like a young Tua Tagovailoa in his first career start for the Golden Bears. Tip of the cap.

Remember, this isn’t the place for locks or five-team parlays. These are the games I’m betting with my own money.

Let’s go to work.

2025 Record: (2-3, -1.4 units)

Illinois (-3, O/U 49) @ Duke

The Illini will continue to be a public darling until they eventually slip up. This will not be an easy game against Manny Diaz’s defense, which usually takes away what you do well. I can’t wait to watch the chess match between Diaz and Illinois quarterback Luke Altmeyer. If Darian Mensah comes to play for Duke, the Blue Devils can pull the upset as a very small underdog.  

PICK: Duke (+3) to lose by fewer than 3 points, or win outright

Will Luke Altmyer lead “public darling” Illinois to a win in Week 2?

Kansas @ Missouri (-6.5, O/U 51)

Don’t sleep on the Jayhawks. Last season didn’t go as planned in Lawrence, but Kansas finished strong down the stretch. Quarterback Jalon Daniels is as healthy as he’s been and the KU defense is better than people realize. You’re still paying a Missouri tax from last year’s 10-3 campaign, too. I think this one goes down to the wire in Columbia between these two rivals.

PICK: Missouri (+6.5) to lose by fewer than 6.5 points, or win outright

Kent State @ Texas Tech (-48, O/U 58.5)

It sounds like Red Raiders quarterback Behren Morton is going to play. Some people will say it “doesn’t matter,” but it does. I want QB1 out there for the first half before head coach Joey McGuire inevitably goes to QB2 Will Hammond for the second half. Kent State is the worst power rated team in the FBS and this is a rout, assuming Texas Tech keeps its foot on the gas.

PICK: Texas Tech (-48) to win by more than 48 points

Las Vegas Raiders @ New England Patriots (-2.5, O/U 44)

Is there a trendier team than the Patriots? Everywhere I look, it’s Drake Maye this and Mike Vrabel that. And some pundits are even predicting a playoff berth. I see a four-win team from last year starting two rookies on the left side of the offensive line and a quarterback operating with minimal weapons. Maybe I’m wrong. Maxx Crosby should have a big day in the trenches.

PICK: Raiders (+2.5) to lose by fewer than 2.5 points, or win outright

Raiders’ defensive end Maxx Crosby will look to have a field day in New England this weekend.

New York Giants @ Washington Commanders (-6, O/U 45.5)

Wise guys cleaned the +7s and +6.5s off the board the last couple of weeks, and it’s difficult to ignore the financial respect for the underdog here. The Commanders are mostly viewed as a playoff team and young quarterback Jayden Daniels has the fifth-shortest odds for NFL MVP. But the Giants have a sneaky good “D” and Russell Wilson has some juice left in the tank.  

PICK: Giants (+6) to lose by fewer than 6 points, or win outright

Sam Panayotovich is a sports betting analyst for FOX Sports and the BetMGM Network. He previously worked for WGN Radio, NBC Sports and VSiN. Follow him on Twitter @spshoot.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, and follow leagues, teams and players to receive a personalized newsletter daily!

What did you consider this story?


really helpful

Merchandise 1 of three


National Football League

Get more from the National Football League Follow your favorites to get information about games, news and more


Subscribe to Our Newsletter
Subscribe to our newsletter to get our newest articles instantly!
[mc4wp_form]
Share This Article
Email Copy Link Print
Previous Article Lots of of South Koreans are amongst 475 detained in a Georgia immigration raid : NPR Lots of of South Koreans are amongst 475 detained in a Georgia immigration raid : NPR
Next Article Orlando Bloom speaks out on Katy Perry breakup: ‘It’s nothing however love’ Orlando Bloom speaks out on Katy Perry breakup: ‘It’s nothing however love’
Leave a Comment

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

POPULAR

Save 50% on each annual plans through the Paramount+ fall sale
Entertainment

Save 50% on each annual plans through the Paramount+ fall sale

Matt Hasselbeck talks Dak Prescott, A.J. Brown's lack of targets, Joe Burrow's early season struggles | FULL INTERVIEW | The Herd
Sports

Matt Hasselbeck talks Dak Prescott, A.J. Brown's lack of targets, Joe Burrow's early season struggles | FULL INTERVIEW | The Herd

Norwalk agrees to repeal homeless shelter ban, AG says
National & World

Norwalk agrees to repeal homeless shelter ban, AG says

Trump to concern government order to permit punishments for international locations wrongfully detaining People
Politics

Trump to concern government order to permit punishments for international locations wrongfully detaining People

S&P 500, Nasdaq, Dow slip after jobs report exhibits dramatic slowdown
Money

S&P 500, Nasdaq, Dow slip after jobs report exhibits dramatic slowdown

Disturbing Case: Mom Bear & Cub Illegally Shot In Humboldt County, California
Pets & Animals

Disturbing Case: Mom Bear & Cub Illegally Shot In Humboldt County, California

Meet the girl who makes certain stars get the VIP remedy on the U.S. Open.
Entertainment

Meet the girl who makes certain stars get the VIP remedy on the U.S. Open.

You Might Also Like

What Can We Count on From Jaguars Two-Approach Star Travis Hunter In Week 1?
Sports

What Can We Count on From Jaguars Two-Approach Star Travis Hunter In Week 1?

In picking Travis Hunter No. 2 overall in the draft, Jaguars general manager James Gladstone said he expected the two-way…

7 Min Read
WATCH: Phillies slugger Kyle Schwarber ties MLB document with 4 house runs in 19-4 rout of Braves
Sports

WATCH: Phillies slugger Kyle Schwarber ties MLB document with 4 house runs in 19-4 rout of Braves

Philadelphia Phillies slugger Kyle Schwarber made historical past on Thursday night time towards the Atlanta Braves (PHI 19, ATL 4) when…

3 Min Read
Mike Tomlin: Steelers protection is able to doing ‘historic issues’ in 2025
Sports

Mike Tomlin: Steelers protection is able to doing ‘historic issues’ in 2025

It is secure to say that Pittsburgh Steelers coach Mike Tomlin is happy with what he has seen from his protection by…

5 Min Read
Cruiserweight Jake Paul and Light-weight Gervonta Davis To Battle on Nov. 14
Sports

Cruiserweight Jake Paul and Light-weight Gervonta Davis To Battle on Nov. 14

YouTuber-turned-cruiserweight boxer Jake Paul and undefeated WBA lightweight champion Gervonta "Tank" Davis have agreed to fight on Nov. 14 at…

4 Min Read
Madisony

We cover the stories that shape the world, from breaking global headlines to the insights behind them. Our mission is simple: deliver news you can rely on, fast and fact-checked.

Recent News

Save 50% on each annual plans through the Paramount+ fall sale
Save 50% on each annual plans through the Paramount+ fall sale
September 5, 2025
Matt Hasselbeck talks Dak Prescott, A.J. Brown's lack of targets, Joe Burrow's early season struggles | FULL INTERVIEW | The Herd
Matt Hasselbeck talks Dak Prescott, A.J. Brown's lack of targets, Joe Burrow's early season struggles | FULL INTERVIEW | The Herd
September 5, 2025
Norwalk agrees to repeal homeless shelter ban, AG says
Norwalk agrees to repeal homeless shelter ban, AG says
September 5, 2025

Trending News

Save 50% on each annual plans through the Paramount+ fall sale
Matt Hasselbeck talks Dak Prescott, A.J. Brown's lack of targets, Joe Burrow's early season struggles | FULL INTERVIEW | The Herd
Norwalk agrees to repeal homeless shelter ban, AG says
Trump to concern government order to permit punishments for international locations wrongfully detaining People
S&P 500, Nasdaq, Dow slip after jobs report exhibits dramatic slowdown
  • About Us
  • Privacy Policy
  • Terms Of Service
Reading: 2025 NFL, CFB Odds: Greatest Bets for Giants-Commanders, Illinois-Duke
Share

2025 © Madisony.com. All Rights Reserved.

Welcome Back!

Sign in to your account

Username or Email Address
Password

Lost your password?