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49ers vs. Seahawks prediction, odds, unfold: 2026 NFL divisional spherical picks by confirmed mannequin

Madisony
Last updated: January 16, 2026 1:38 pm
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49ers vs. Seahawks prediction, odds, unfold: 2026 NFL divisional spherical picks by confirmed mannequin
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Why the Seahawks can cowlWhy the 49ers can cowlHow one can make 49ers vs. Seahawks picks

Division rivals sq. off with a spot within the NFC Championship Recreation on the road when the San Francisco 49ers battle the Seattle Seahawks within the 2026 NFL divisional spherical on Saturday. San Francisco (12-5) superior with a 23-19 wild-card win at Philadelphia, whereas Seattle (14-3) is coming off a bye after incomes the NFC’s high seed. These groups break up their two head-to-head matchups within the common season. Seattle quarterback Sam Darnold (indirect) is listed as questionable, however informed reporters that he’ll play. Niners receiver Ricky Pearsall (knee) is questionable. 

Kickoff from Lumen Subject in Seattle is about for 8 p.m. ET. The Seahawks are 7-point favorites within the newest 49ers vs. Seahawks odds, whereas the over/beneath for whole factors scored is 44.5 by way of DraftKings Sportsbook. Earlier than making any Seahawks vs. 49ers picks, take a look at the NFL predictions from the SportsLine Projection Mannequin. 

The mannequin, which simulates each NFL sport 10,000 instances, is up properly over $7,000 for $100 gamers on top-rated NFL picks since its inception. The mannequin enters the divisional spherical of the 2026 NFL playoffs on a 53-37 run on top-rated picks relationship again to 2024. Anyone following its NFL betting picks at sportsbooks and on betting websites may have seen sturdy returns.    

Now, the mannequin has set its sights on 49ers vs. Seahawks. You may go to SportsLine now to see the picks. Listed below are the NFL odds and traits for Seahawks vs. Niners:

49ers vs. Seahawks unfold

Seattle -7 at DraftKings Sportsbook

49ers vs. Seahawks over/beneath

44.5 factors

49ers vs. Seahawks cash line 

Seattle -340, San Francisco +270

49ers vs. Seahawks picks

See picks at SportsLine

49ers vs. Seahawks streaming 

Fubo (Attempt without cost)  

Why the Seahawks can cowl

Eighth-year veteran Sam Darnold helps energy the Seattle offense. In 17 video games, he has accomplished 67.7% of his passes for 4,048 yards and 25 touchdowns with 14 interceptions and a 99.1 score. In a 13-3 win over the 49ers on Jan. 3, he accomplished 20 of 26 passes for 198 yards. In a 38-37 come-from-behind additional time win over the Los Angeles Rams on Dec. 18, he accomplished 22 of 34 passes for 270 yards and two touchdowns with two interceptions.

His high goal is third-year veteran huge receiver Jaxon Smith-Njigba. In 17 video games, he caught 119 passes for 1,793 yards (15.1 common) and 10 touchdowns. He had 27 explosive performs of 20 yards or extra, together with an extended of 63, with 528 yards after the catch and 79 first-down conversions. In two video games in opposition to San Francisco this season, he caught 15 passes for 208 yards. See which group to again at SportsLine. 

Why the 49ers can cowl

Fourth-year veteran quarterback Brock Purdy is coming off a stable efficiency within the Wild Card win over Philadelphia. He accomplished 18 of 31 passes for 262 yards and two touchdowns with two interceptions. In 9 regular-season video games this 12 months, he accomplished 69.4% of his passes for two,167 yards and 20 touchdowns with 10 interceptions and a 100.5 score. He additionally carried 33 instances for 147 yards (4.5 common) and three scores.

Veteran Christian McCaffrey was San Francisco’s main rusher and receiver through the common season. In 17 video games, he carried 311 instances for 1,202 yards and 10 touchdowns. He additionally had 102 receptions for 924 yards (9.1 common) and 7 touchdowns with seven explosive performs, together with an extended of 39, with 720 yards after the catch and 49 first-down conversions. Within the Wild Card win at Philadelphia, he carried 15 instances for 48 yards (3.2 common) and had six receptions for 66 yards and two touchdowns. See which group to again at SportsLine.

How one can make 49ers vs. Seahawks picks

SportsLine’s mannequin goes Over on the overall, projecting 49 mixed factors. It additionally says one facet of the unfold is the higher worth. You may solely get the choose at SportsLine. 

So who wins Seahawks vs. 49ers, and which facet of the unfold is the higher worth? Go to SportsLine now to see which facet of the 49ers vs. Seahawks unfold to leap on, all from the superior mannequin that completed up over $7,000 on its NFL picks since its inception, and discover out.

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