U.S. President Donald Trump speaks throughout an occasion within the Roosevelt Room of the White Home December 19, 2025 in Washington, DC. Trump delivered remarks on decreasing prescription drug costs through the occasion.
Alex Wong | Getty Photos
A number of of the most important U.S. and European-based drugmakers inked offers with President Donald Trump on Friday to voluntarily promote their drugs for much less, as his administration pushes to hyperlink the nation’s drug costs to cheaper ones overseas.
That features Merck, Bristol Myers Squibb, Amgen, Gilead, GSK, Sanofi, Roche‘s Genentech, privately-held Boehringer Ingelheim and Novartis. In change, the businesses agreed to a three-year grace interval throughout which their merchandise will not face Trump’s deliberate pharmaceutical-specific tariffs – so long as the drugmakers additional put money into U.S. manufacturing.
Among the many most notable pledges on Friday is that Bristol Myers Squibb will provide Eliquis, its blockbuster blood thinner and top-prescribed product, free of charge to Medicaid.
The businesses make up the vast majority of the 17 drugmakers Trump despatched letters to in July, calling on them to decrease costs as a part of his “most favored nation” coverage. Trump signed an government order in Might to revive that coverage, calling for costs to be elevated exterior of the U.S. and to “finish world freeloading.”
“As of at present, 14 out of the 17 largest pharmaceutical firms … have now agreed to drastically decrease drug costs for … the American folks and the American sufferers,” Trump stated at an occasion on Friday. “This represents the best victory for affected person affordability within the historical past of American well being care, by far, and each single American will profit.”
Johnson & Johnson, AbbVie and Regeneron are the remaining firms among the many largest that have not signed drug pricing offers. However Trump famous that Johnson & Johnson “will likely be right here subsequent week.”
How the drug pricing offers will work
The complete phrases of the offers weren’t instantly launched, which makes it unclear how broad their impression will likely be.
The 9 drugmakers agreed to take measures to cut back U.S. drug costs, together with promoting their current remedies to Medicaid sufferers on the lowest “most favored nation” costs, and guaranteeing that pricing for brand new medicines. Trump stated the drugmakers additionally agreed to checklist their hottest medicine on his upcoming direct-to-consumer web site, TrumpRx, which is launching in January.
Some firms additionally launched new or expanded current direct-to-consumer choices for sure medicine. For instance, Gilead stated in a launch that it’s going to launch a program that can enable sufferers to entry its Hepatitis C remedy and treatment, Epclusa, at a reduced worth.
Sanofi stated it should provide reductions of almost 70% on sure medicines to deal with infections and cardiovascular and diabetic situations on TrumpRx and different direct-to-consumer platforms.
Merck stated it should provide three diabetes drugs, Januvia, Janumet and Janumet XR, at a roughly 70% low cost to cash-paying sufferers via a direct-to-patient program. That program will likely be prolonged to the corporate’s experimental every day ldl cholesterol tablet if it will get permitted within the U.S., in accordance with the corporate.
“I mirror in your purpose of driving affordability and entry to People, however equally, getting costs up exterior america,” Merck CEO Robert Davis stated through the press convention. “And we’re 100% supportive of your actions.”
In the meantime, Amgen will develop its current direct-to-patient program to incorporate preventative migraine remedy Aimovig and autoimmune remedy Amjevita, at 60% and 80% discounted month-to-month costs, respectively.
Earlier this yr, Trump introduced agreements with Eli Lilly, Novo Nordisk, Pfizer, AstraZeneca and EMD Serono to promote sure medicine on to sufferers at a reduction, in change for exemptions from his deliberate pharmaceutical tariffs and different advantages, akin to fast-tracked critiques of latest medicine.
U.S. prescription drug costs on common are almost thrice larger than abroad, in accordance with a 2024 research by RAND Company. Costs for branded medicine have been greater than 4 occasions larger, the report discovered.
Trump signed an government order in Might to revive probably the most favored nation coverage, calling for costs to be elevated exterior of the U.S. and to “finish world freeloading.”
Commerce affiliation PhRMA, which represents many main pharma firms, has stated that most-favored nation pricing is not the easiest way to decrease drug prices for People, and as an alternative blamed pharmacy profit managers for the value disparity.
The U.S. is the one most vital market for a lot of drugmakers, no matter their house nation. Regardless of being based mostly throughout the Atlantic, European pharma firms are closely uncovered to the U.S. market, with half of the ten largest firms on the continent producing a majority of their gross sales within the U.S.
