You’ve got waited a very long time to listen to this, and the day has lastly arrived: The NFL is again! Week 1 is already underway after the Philadelphia Eagles and Dallas Cowboys received us began on Thursday night time, and we now have a whole Sunday slate in entrance of us. What a time to be alive!
As we’ll do each week all through the season, we have collected the entire greatest picks and playing content material from CBS Sports activities and SportsLine and put them in a single place, so you will get picks towards the unfold from our CBS Sports activities consultants in addition to extra function content material for every recreation, together with performs from high SportsLine consultants and the SportsLine Projection Mannequin, greatest bets from our employees, survivor picks and extra. Prepared? Let’s leap in.
All NFL odds by way of SportsLine consensus odds.
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Chiefs at Chargers
Friday, 8 p.m. ET on YouTube
SportsLine knowledgeable Mike Tierney, who was 61-39-3 on his NFL picks in 2024, has zeroed in on this matchup between the Chiefs and Chargers from Sao Paulo, Brazil. We will let you know that Tierney is leaning beneath the 45.5 level whole, however he has dialed in an ATS wager that could be a must-see earlier than putting any wager. To verify that out, click on on over to SportsLine.
“I totally count on that each quarterbacks will probably be going through fixed strain on this recreation, and in that state of affairs, I belief Mahomes barely greater than I belief Justin Herbert. OK, much more. Each staff that has ever received in Brazil has gone on to win the Tremendous Bowl that yr, in order that looks as if an excellent factor for the Chiefs.” — CBS Sports activities NFL author John Breech on why he likes the Chiefs to win the opener, 23-20. To see all of his Week 1 picks, click on right here.
Buccaneers at Falcons
Sunday, 1 p.m. ET on Fox (Stream: Fubo — strive totally free)
Buccaneers -1.5: “The Bucs are the favorites within the division, however the Falcons are thought of the highest risk. That makes this a giant opener. Each groups have accidents on their offensive strains, which might impression the sport, however I believe Baker Mayfield is prepared for a giant yr. The Falcons nonetheless have some defensive questions, which is able to present up. Michael Penix Jr. will not sustain. Bucs take it.” — CBS Sports activities senior NFL author Pete Prisco on why he has the Bucs taking down the Falcons, 28-24. Click on right here to see all of Prisco’s Week 1 picks.
Bijan Robinson Over 22.5 receiving yards: “Of us could be scared off as a result of Bijan Robinson averaged a measly 6.7 receiving yards per recreation within the three video games Michael Penix Jr. began on the finish of the yr, however Robinson’s 4 targets have been nonetheless roughly in keeping with his pre-Penix numbers, in order that output could also be an anomaly. He additionally will get a positive matchup towards the Buccaneers, who surrendered the fifth-most receiving yards to backs final season.” — CBS Sports activities NFL author Tyler Sullivan on why he likes that prop for Robinson. To see Sullivan’s different high participant props for Week 1, click on right here.
Bengals at Browns
Sunday, 1 p.m. ET on Fox (Stream: Fubo — strive totally free)
Browns +5.5: “The battle of Ohio is at all times fascinating, and this one must be no totally different. That is Joe Flacco towards Joe Burrow, which is a giant edge for the Bengals. They need to proceed the place they left off final yr, rolling up huge offensive numbers. The protection has questions, however the Browns will not be capable of sustain. It is shut, however Burrow wins it.” — Pete Prisco on why he has the Bengals taking down the Browns, 30-27. Click on right here to see all of Prisco’s Week 1 picks.
Dolphins at Colts
Sunday, 1 p.m. ET on CBS (Stream on Paramount+)
Colts -1.5: “This will probably be Daniel Jones making his Colts debut at quarterback towards a Miami secondary that is not precisely full of premier playmakers at nook. It is an incredible probability for Jones. The Dolphins ought to be capable of have success throwing it on the opposite facet, particularly if Tyreek Hill is again wholesome. Search for a high-scoring recreation, with the Colts discovering a approach at dwelling.” — Pete Prisco on why he likes the Colts to take down the Dolphins, 33-30. Click on right here to see all of Prisco’s Week 1 picks.
Raiders at Patriots
Sunday, 1 p.m. ET on CBS (Stream on Paramount+)
Raiders +3: “The central purpose why I like taking Las Vegas on this spot is because of a key power of the Patriots — the secondary — being banged up. Particularly, All-Professional nook Christian Gonzalez has been sidelined for the majority of camp because of a hamstring harm and will not swimsuit up. That might permit Geno Smith simpler passing lanes on this street matchup.” — Tyler Sullivan on why he has the Raiders overlaying on the street towards New England. To see all of his Week 1 picks, click on right here.
Cardinals at Saints
Sunday, 1 p.m. ET on Fox (Stream: Fubo — strive totally free)
Need to dominate your Survivor Pool? Look no additional than SportsLine knowledgeable R.J. White. He has constructed a number of NFL survivor roadmaps that will help you navigate by way of the 2025 marketing campaign with ease and outlast the competitors. A kind of paths begins with this matchup in New Orleans on Sunday. To see White’s full roadmap and which approach he’s rolling on this matchup, go take a look at SportsLine.
Steelers at Jets
Sunday, 1 p.m. ET on CBS (Stream on Paramount+)
Jets +3: “I’ve main questions on how this newest Aaron Rodgers experiment will go along with the Steelers. On title worth, it is a slam dunk acquisition, however Rodgers is coming off his worst statistical season of his profession and is 41 years previous. When he received sizzling down the stretch, it was largely because of his rapport with previous buddy Davante Adams. Rodgers would not have that inbuilt chemistry with anybody within the Steelers go pass-catching group, and I count on the offense to look a bit clunky out of the gate. In spite of everything, Rodgers signed simply earlier than minicamp and did not participate in any preseason motion, so he hasn’t had his toes held to the hearth a lot with this group.” — Tyler Sullivan on why he not solely likes the Jets to cowl, but in addition to drag off the house upset. To see all of his Week 1 picks, click on right here.
Giants at Commanders
Sunday, 1 p.m. ET on Fox (Stream: Fubo — strive totally free)
The SportsLine Projection Mannequin — which is at present hitting at a 67% success fee coming into Week 1 on top-rated NFL picks — has revealed its 25-1 parlay for the season-opening slate. Throughout the parlay contains the Commanders overlaying the 6-point unfold over the Giants at dwelling. That choice covers in 60% of simulations and is an A-rated decide, in accordance with the mannequin. One another leg is hitting on greater than 50% of simulations, together with an ATS decide that’s overlaying at a outstanding 63% fee. To see the remainder of the legs to finish this parlay, head on over to SportsLine.
Panthers at Jaguars
Sunday, 1 p.m. on Fox (Stream: Fubo — strive totally free)
Jaguars -3: “That is the debut for Jaguars head coach Liam Coen, who ought to brighten up the offense. Search for Trevor Lawrence to play nicely right here and regulate the Travis Hunter utilization. The Panthers be ok with Bryce Younger after final season, however I believe the Jaguars get the perfect of him right here. Jaguars take it.” — Pete Prisco on why he likes Jacksonville to outlast the Panthers, 27-21. Click on right here to see all of Prisco’s Week 1 picks.
Brenton Unusual anytime landing: “The Jaguars offense goes to focus on their immensely gifted receiver duo of Brian Thomas Jr. and Travis Hunter. Nevertheless, do not sleep on tight finish Brenton Unusual being an element within the passing recreation. As we noticed with Evan Engram prior to now, Trevor Lawrence can pepper the tight finish place when he drops again, and the arrival of head coach Liam Coen solely emboldens Unusual to interrupt out in 2025, starting in Week 1. … Plus, Unusual will get a positive matchup out of the gate with a Panthers protection that surrendered probably the most receiving touchdowns (11) to tight ends in 2024.” — Tyler Sullivan on why he likes Unusual to seek out the top zone in Week 1. To see his different high participant props for Week 1, click on right here.
Titans at Broncos
Sunday, 4:05 p.m. on Fox (Stream: Fubo — strive totally free)
Broncos -7.5: “This will probably be Cameron Ward’s first NFL begin for the Titans, and he is making it towards one of many league’s greatest defenses in one of many hardest locations to play. That is robust sledding. I search for Bo Nix to have success throwing it for Denver on the opposite facet. The Broncos get off to a quick begin, whereas the protection closes the door by limiting Ward.” — Pete Prisco on why he has the Broncos taking down the Titans, 26-13. Click on right here to see all of Prisco’s Week 1 picks.
49ers at Seahawks
Sunday, 4:05 p.m. on Fox (Stream: Fubo — strive totally free)
49ers -2.5: “The 49ers have received seven of the final eight on this collection, however Seattle received the final one final November. These groups are loads totally different now. The 49ers have been banged up final yr, however Christian McCaffrey and left deal with Trent Williams are two of their stars who’re again. That may matter. The Seahawks can have Sam Darnold making his first begin at quarterback. It is at all times robust to play at Seattle, however the 49ers know win there. They are going to once more.” — Prisco on why he has the Niners defeating the Seahawks, 23-17. Click on right here to see all of Prisco’s Week 1 picks.
Lions at Packers
Sunday, 4:25 p.m. on CBS (Stream on Paramount+)
Lions +1.5: “Primarily based on Parsons’ again state of affairs, I will be shocked if he is on the sphere for even 1 / 4 of the Packers’ defensive performs on this recreation, so mainly, for at the least this week, I do not suppose Parsons goes to have a big impact. Final season, the Packers have been both the perfect dangerous staff or the worst good staff. I’ve had 9 months to consider it and I am nonetheless unsure. They went 11-1 towards groups that completed with 10 wins or much less, however 0-6 towards groups that received 11 video games or extra. Additionally they went simply 1-5 within the NFC North. One downside for the Packers is that Matt LaFleur hasn’t been ready to determine beat the Lions with Detroit profitable six of the previous seven video games on this collection.
“The Lions positively have some query marks — they’ve to interchange each coordinators, they’ve a rookie at proper guard (Tate Ratledge) and their beginning middle retired — however they may have Aidan Hutchinson again, and I really feel like his return will push Detroit to the win. The Lions have received three straight in Inexperienced Bay, and in the event that they win this recreation, they could as nicely change the title of the stadium to “Lionbeau area.” And sure, I am already working to trademark that.” — CBS Sports activities NFL author John Breech on why he has the Lions defeating the Packers, 20-16. To see all of his Week 1 picks, click on right here.
Texans at Rams
Sunday, 4:25 p.m. on CBS (Stream on Paramount+)
Texans +2.5: “So Stafford has a foul again and oh yea, he nonetheless hasn’t TAKEN A HIT this yr, so we do not know how his again goes to deal with that. If in case you have a foul again, the Texans are most likely the final staff you wish to be going through in Week 1. There have been solely 11 gamers within the NFL final season who totaled 11 sacks or extra and two of these guys are on Houston’s protection (Will Anderson Jr. and Danielle Hunter).
“The Texans even have one of many few secondaries within the NFL that ought to be capable of go toe-to-toe with Davante Adams and Puka Nacua, so even when Stafford’s again holds up, do not count on him to place up huge numbers. The opposite factor to love concerning the Texans is that head coach DeMeco Ryans may be very familar with Sean McVay’s offense. Ryans spent two seasons because the 49ers’ defensive coordinator and through these two years, the 49ers had a 4-0 regular-season report towards the Rams whereas holding McVay’s offense to simply 14.25 factors per recreation.” — John Breech on why he has the Texans defeating the Rams, 19-17. To see all of his Week 1 picks, click on right here.
Ravens at Payments
Sunday, 8:20 p.m. on NBC (Stream: Fubo — strive totally free)
Earlier than you dive into this heavyweight showdown between two of the AFC’s elite, you could see how SportsLine knowledgeable Mike Tierney is assault this recreation. In spite of everything, Tierney was 61-39-3 on his NFL picks in 2024, and he is seeking to deliver that sizzling streak into 2025. We will let you know he’s leaning Below the 50.5 level whole, however to see who he’s backing towards the unfold, you may must go to SportsLine.
Vikings at Bears
Monday, 8:15 p.m. ET on ABC/ESPN (Stream: Fubo — strive totally free)
Bears +1.5: “I have been on report saying that the Vikings are arguably the best-equipped staff to usher in a quarterback like J.J. McCarthy. Between a stout protection, elite offensive weapons, and a stellar head coach in Kevin O’Connell, it ought to enormously assist pace his growth alongside. However making him a street favourite towards a divisional opponent appears a bit wealthy at this stage. McCarthy’s final significant snap got here again throughout his days at Michigan within the Faculty Soccer Playoff Nationwide Championship. And he is anticipated to now enter Soldier Area and pull out a street win? Once more, feels wealthy. Oh, and the Vikings are 0-6 of their final six street prime-time video games.” — Tyler Sullivan on why he likes the Bears to drag off the house upset over the Vikings. To see all of Sullivan’s Week 1 picks, click on right here.