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Prisco’s Week 2 NFL picks: Chiefs get revenge on Eagles, will Lions and Ravens bounce again?

Madisony
Last updated: September 14, 2025 9:20 am
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Prisco’s Week 2 NFL picks: Chiefs get revenge on Eagles, will Lions and Ravens bounce again?
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Let’s go.

A successful week. What have you learnt? 

After final season’s terrible displaying, it is good to sit down right here and brag a few successful document in Week 1 of the NFL season choosing video games, each in opposition to the unfold and straight up. I went 13-3 straight up and 11-5 ATS final week. I will take it. 

Let’s maintain the momentum rolling into Week 2. Simply keep in mind as you make your picks this week, no person is pretty much as good as they seemed final week and no person is dangerous as they seemed. Some even name Week 2 the get-even week. So watch out and let’s hope my Week 1 success wasn’t an aberration, however slightly turns into the norm.

Wager NFL Week 2 video games and NFL odds at DraftKings, the place new customers get $300 in bonus bets and over $200 off NFL Sunday Ticket. Click on right here to get began:

Cleveland Browns at Baltimore Ravens (-11.5)

Sunday, 1 p.m. on CBS (Stream on Paramount+)

The Ravens might be seeking to bounce again from a brutal loss to the Payments on Sunday evening. It is exhausting to get previous that, however this crew and this coach can do it. The Browns performed effectively on protection in opposition to the Bengals, however that is one other robust problem. The Ravens will get again on monitor. 

Decide: Ravens 30, Browns 17 | Odds by way of Caesars Sportsbook

Sunday, 1 p.m. on CBS (Stream on Paramount+)

This can be a sport that includes two groups who gained final week, with the Jaguars being the extra spectacular of the 2. The Bengals offense struggled in opposition to Cleveland, whereas the protection performed effectively. I search for the Jaguars to hold round on this one, however Joe Burrow will win it late. 

Decide: Bengals 24, Jaguars 23 | Odds by way of BetMGM

Sunday, 1 p.m. on Fox (Stream: Fubo — attempt free of charge)

Russell Wilson and the Giants are on the highway for the second consecutive week in opposition to a crew with added relaxation taking part in its house opener. That is a brutal problem. Nevertheless it’s even worse as a result of Wilson struggled in Week 1. Dak Prescott didn’t. The Cowboys will get their first victory right here as Prescott performs effectively. 

Decide: Cowboys 28, Giants 17 | Odds by way of DraftKings Sportsbook

Sunday, 1 p.m. on Fox (Stream: Fubo — attempt free of charge)

The Bears are on the highway off a brief week in opposition to the Lions coming off a highway loss. The Lions did not look good within the loss to the Packers, however now they will get the offense going in opposition to a Bears protection that collapsed within the fourth quarter in opposition to the Vikings. The Lions win it. 

Decide: Lions 30, Bears 17 | Odds by way of FanDuel Sportsbook

Sunday, 1 p.m. on CBS (Stream on Paramount+)

Each of those groups are coming off dangerous losses in Week One. The Dolphins seemed hapless. However I feel that modifications right here. Tua Tagovailoa will play effectively at house because the Dolphins get again on monitor. Mike McDaniel higher hope they do. 

Decide: Dolphins 27, Patriots 19 | Odds by way of Caesars Sportsbook

Sunday, 1 p.m. on Fox (Stream: Fubo — attempt free of charge)

This can be a banged-up 49ers crew, which might be with out George Kittle and could possibly be with out quarterback Brock Purdy. That might be a problem to win if Mac Jones performs. The Saints pushed the Cardinals final week and I feel they’ll hold round right here in addition to the 49ers play consecutive highway video games. 

Decide: 49ers 22, Saints 20 | Odds by way of FanDuel Sportsbook

Sunday, 1 p.m. on CBS (Stream on Paramount+)

This can be a robust spot for the Payments coming off their comeback victory over the Ravens on Sunday evening and now taking part in a crew from their division that misplaced at house. Josh Allen has had troubles on this stadium in opposition to this crew, and this might be no totally different because the Jets protection performs effectively. It is shut, however Allen will win it late. 

Decide: Payments 24, Jets 21 | Odds by way of Caesars Sportsbook

Sunday, 1 p.m. on Fox (Stream: Fubo — attempt free of charge)

The Steelers are taking part in the house opener in opposition to a Seattle crew that misplaced a tricky one to the 49ers final week. Aaron Rodgers seemed good in opposition to the Jets and I feel that may carry over right here. The Steelers will go to 2-0 as Rodgers performs effectively and DK Metcalf does some harm to his former crew. 

Decide: Steelers 26, Seahawks 19 | Odds by way of FanDuel Sportsbook, the place new customers get $300 in bonus bets with a successful $5 wager:

Los Angeles Rams (-5.5) at Tennessee Titans

Sunday, 1 p.m. on CBS (Stream on Paramount+)

The Titans confirmed effectively on protection final week, which is able to make this fascinating for a Rams offense that did not do a lot of their victory over the Texans. Tennessee’s offense struggled too, however now Cam Ward is house after shedding at Denver. I feel he’ll play higher, nevertheless it’s the protection that maintain the Titans in it. Rams will win an in depth one. 

Decide: Rams 21, Titans 17 | Odds by way of Caesars Sportsbook, the place new customers get 20 100% revenue boosts with the code CBS20X:

Sunday, 4:05 p.m. on CBS (Stream on Paramount+)

Carolina is taking part in consecutive highway video games, whereas the Cardinals are taking part in their house opener. The Panthers struggled on offense final week within the loss to the Jaguars and I can not see it wanting a lot better right here. Kyler Murray and the Cardinals will transfer the ball on the Carolina protection to win it. 

Decide: Cardinals 30, Panthers 17 | Odds by way of FanDuel Sportsbook

Sunday, 4:05 p.m. on CBS (Stream on Paramount+)

Denver is out on the highway for the primary time in opposition to a Colts crew that dominated the Dolphins final week. Daniel Jones performed effectively in that sport. However this can be a a lot more durable problem within the Denver protection. Bo Nix wasn’t nice final week, so he must get again on monitor. I feel the Colts will discover a strategy to win this one late. 

Decide: Colts 24, Broncos 23 | Odds by way of Caesars Sportsbook

Sunday, 4:25 p.m. on Fox (Stream: Fubo — attempt free of charge)

This rematch of the final February’s Tremendous Bowl might be a enjoyable one to look at. The Chiefs are coming off a tricky loss to the Chargers in Brazil, whereas the Eagles edged the Cowboys of their season opener. Philadelphia’s move rush gained the Tremendous Bowl for the Eagles, however the Chiefs are higher up entrance. That may matter as Patrick Mahomes wins it with a late comeback. 

Decide: Chiefs 30, Eagles 28 | Odds by way of FanDuel Sportsbook, the place new customers get $300 in bonus bets with a successful $5 wager:

Sunday, 8:20 p.m. on NBC (Stream: Fubo — attempt free of charge)

The Falcons misplaced a tricky one at house to the Bucs, whereas the Vikings rallied to beat the Bears. J.J. McCarthy performed effectively within the fourth quarter to steer the Vikings again. The Falcons did some good issues on offense, and I feel that may maintain them on this one with one other stable displaying. Vikings will win an in depth one, however Michael Penix Jr. will maintain his crew in it.  

Decide: Vikings 23, Falcons 21 | Odds by way of Caesars Sportsbook

Monday, 7 p.m. ET on ABC, ESPN (Stream: Fubo — attempt free of charge)

The Bucs are taking part in back-to-back highway video games, whereas the Texans are taking part in their house opener. That is by no means a very good mixture. However the Texans have offensive line points that could possibly be at play on this one. Even so, I feel the Texans will discover a approach behind their dominant protection to win this one. 

Decide: Texans 23, Bucs 17 | Odds by way of BetMGM

Monday, 10 p.m. ET on ESPN (Stream: Fubo — attempt free of charge)

The Raiders are house for the primary time, whereas the Chargers are again out on the highway after beating the Chiefs in Brazil. Chargers quarterback Justin Herbert was excellent in that sport, which I feel will proceed right here. Raiders quarterback Geno Smith performed effectively in his crew’s victory over the Patriots, so search for him to maintain up with Herbert. The Chargers will win a decent shootout.  

Decide: Chargers 31, Raiders 30 | Odds by way of FanDuel Sportsbook



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Reading: Prisco’s Week 2 NFL picks: Chiefs get revenge on Eagles, will Lions and Ravens bounce again?
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