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Reading: NFL parlay for Week 5 that might return 25-1 from SportsLine’s confirmed mannequin
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Sports

NFL parlay for Week 5 that might return 25-1 from SportsLine’s confirmed mannequin

Madisony
Last updated: September 30, 2025 4:35 pm
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NFL parlay for Week 5 that might return 25-1 from SportsLine’s confirmed mannequin
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Prime Week 5 NFL picksmake Week 5 NFL parlays

The Buffalo Payments can seize full management of the AFC East after they tackle the New England Patriots on Sunday Night time Soccer. A win would give Buffalo a three-game lead over the second-place Patriots simply 5 weeks into the season. Ever since rallying for a 41-40 win over the Baltimore Ravens within the season opener, the Payments have dominated. The mannequin is excessive on Buffalo (-8.5, 50.5) to cowl towards the visiting Patriots. New England leads the all-time collection 79-51-1, however the Payments have received eight of the previous 11 conferences.  

There are a variety of intriguing matchups on the Week 5 NFL schedule, together with Vikings vs. Browns (+3.5), Texans vs. Ravens (-3.5), Raiders vs. Colts (-6.5), Cowboys vs. Jets (+2.5), Lions vs. Bengals (+10) and Chiefs vs. Jaguars (+3.5) on Monday Night time Soccer. Which workforce has worth to incorporate in Week 4 NFL bets, and which aspect of the NFL unfold must you goal? Earlier than locking in any Week 5 NFL picks or NFL parlays, you should definitely see the NFL predictions and betting recommendation from SportsLine’s confirmed pc mannequin.

New customers may also goal the DraftKings promo code, which gives $200 in bonus bets immediately in case your guess wins:

The mannequin, which simulates each NFL recreation 10,000 occasions, is up nicely over $7,000 for $100 gamers on top-rated NFL picks since its inception. The mannequin is on a scorching 39-19 run on top-rated picks relationship again to 2024. Anyone following its NFL betting picks at sportsbooks and on betting websites may have seen robust returns.

Now, the mannequin has scoured the Week 5 NFL odds and locked in 5 assured NFL finest bets. Should you efficiently parlay its picks, you would be an enormous payout of round 25-1. You’ll be able to solely see the mannequin’s Week 5 NFL picks at SportsLine.

New customers may also try the newest FanDuel promo code and get $300 in bonus bets immediately at FanDuel in case your $5 guess wins:

Prime Week 5 NFL picks

After simulating each recreation 10,000 occasions, the mannequin is excessive on the Minnesota Vikings (-3.5, 36.5) to cowl towards the Cleveland Browns. The Vikings are hoping to problem for the NFC North Division crown and have Tremendous Bowl aspirations so long as they’ll get wholesome. Beginning quarterback J.J. McCarthy (leg) is anticipated to overlook one more recreation, with Carson Wentz operating the offense. Wentz has stuffed in admirably, finishing 44 of 66 passes (66.7%) for 523 yards and 4 touchdowns with two interceptions.

Within the floor recreation, operating again Jordan Mason leads the Vikings with Aaron Jones being sidelined with a hamstring harm. Mason has carried 56 occasions for 271 yards (4.8 common) and two touchdowns. He has additionally caught six passes for 30 yards. In a 48-10 win over the Bengals on Sept. 21, he carried 16 occasions for 116 yards and two scores. The mannequin has Minnesota profitable and masking in almost 60% of simulations. See which different NFL parlay picks to make right here, and guess the Vikings to cowl right here:

make Week 5 NFL parlays

The mannequin additionally jumped on 4 different NFL matchups the place it says the road is approach off, together with backing an underdog that it says is not going to solely cowl, however win outright. You’ll be able to solely see the mannequin’s Week 5 NFL finest bets and NFL parlay at SportsLine.

What are the mannequin’s high Week 5 NFL picks, and which NFL matchups must you goal for an epic 25-1 payout? Go to SportsLine now to see the Week 5 NFL finest bets from a mannequin on an 39-19 run on top-rated picks, and discover out.



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Reading: NFL parlay for Week 5 that might return 25-1 from SportsLine’s confirmed mannequin
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