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Money

Why Avidity Biosciences And Dyne Therapeutics Shares Soared 40% Monday

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Last updated: October 29, 2025 3:56 am
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Why Avidity Biosciences And Dyne Therapeutics Shares Soared 40% Monday
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Avidity Biosciences is being purchased by Novartis in a $12 billion deal.

  • Novartis is shopping for Avidity Biosciences in an all-cash deal valued at $12 billion to entry Avidity’s experimental remedies for neuromuscular illnesses.

  • The acquisition worth of $72 per share is a 46.5% premium to Avidity’s closing worth Friday.

  • Avidity inventory was up greater than 40% in noon buying and selling Monday, as have been shares of Dyne Therapeutics, which can be growing RNA therapies for neuromuscular illnesses.

Shares of Avidity Biosciences (RNA) soared greater than 40% Monday after Novartis (NVS) agreed to purchase the U.S. biopharmaceutical agency for about $12 billion in money to broaden its RNA-based disease-fighting pipeline.

The Swiss-based drugmaker mentioned Avidity buyers could be paid $72 for each share they owned, a 46.5% premium to Avidity’s closing worth Friday. It famous that previous to completion of the sale, Avidity will spin off its early stage precision cardiology applications into a brand new firm.

With this acquisition, Novartis is increasing its footprint in RNA-based therapies. The deal provides the corporate entry to late-stage remedies for severe neuromuscular illnesses. The deal illustrates rising investor and trade curiosity in RNA therapeutics.

The acquisition provides Novartis entry to 3 of Avidity’s late-stage experimental remedies for severe genetic neuromuscular illness, which use RNA therapeutics known as Antibody Oligonucleotide Conjugates, or AOC.

Including Avidity’s AOC platform ​and its late-stage belongings will “bolster our dedication to delivering progressive, focused and probably first-in-class medicines to deal with devastating, progressive neuromuscular illnesses,” mentioned Novartis CEO Vas Narasimhan. The transaction is anticipated to shut within the first half of subsequent yr.

The corporate believes that the acquisition will enhance its 2024 to 2029 gross sales compound annual development charge from 5% to six%.

In the meantime, shares of Dyne Therapeutics (DYN) skyrocketed greater than 40% Monday after analysts at Jefferies mentioned the corporate, which is also growing RNA therapies for neuromuscular illnesses, stands to profit from Novartis choosing up Avidity.

With the positive aspects Monday, Avidity shares have risen 140% because the begin of the yr, whereas Dyne inventory has inched again into constructive territory. U.S.-listed shares of Novartis, which have gained a few third of their worth to this point this yr, have been down 1% in current buying and selling.

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