Two units of division leaders conflict to headline the NFL Week 10 schedule. On Sunday, the AFC East-leading New England Patriots, led by quarterback Drake Maye, battle the NFC South-leading Tampa Bay Buccaneers and quarterback Baker Mayfield. On ‘Monday Evening Soccer,’ Jalen Hurts leads the Philadelphia Eagles into Lambeau Subject to face Jordan Love and the Inexperienced Bay Packers. Each Tampa Bay and Inexperienced Bay enter as 2.5-point favorites. One other matchup involving contenders sees the Los Angeles Rams (6-2) touring to San Francisco to face the 49ers (6-3) in a key NFC West matchup.
The Rams are 4.5-point favorites as Matthew Stafford appears to be like to avenge a 26-23 additional time loss to San Francisco on Oct. 2. He has gained three of his final 4 begins towards the 49ers. The most important remaining unfold on the percentages board is Buffalo -9.5 vs. Miami. The sport with essentially the most line motion has been Jets vs. Browns, with Cleveland shifting from a 2.5-point underdog to 2.5-point favourite after New York unloaded Sauce Gardner and Quinnen Williams in separate trades earlier than the commerce deadline.
Earlier than making any Week 10 NFL picks or NFL rating predictions on these video games or others, you must see the NFL towards the unfold, over/beneath and cash line predictions powered by the self-learning SportsLine AI.
New customers can goal the DraftKings promo code, which presents $300 in bonus bets in case your guess wins + 3 months of NBA League Go:
Constructed utilizing cutting-edge synthetic intelligence and machine studying strategies by SportsLine’s Information Science group, AI Predictions and AI Scores are generated for every sport. The AI predictions are decided by statistically studying from every group’s historic information after which quantitatively evaluating the power of the opponent’s protection by assigning a numeric worth out of 100 known as a matchup rating. It repeatedly refreshes on the newest accessible information and may help you notice the most important discrepancies within the strains. SportsLine’s AI PickBot has hit greater than 2,000 4.5- and 5-star prop picks because the begin of the 2023 season.
For Week 10 NFL betting, the AI PickBot has evaluated the NFL odds and supplied NFL betting picks for all 14 video games. You possibly can solely see the AI predictions for the Week 10 NFL schedule right here.
New customers may goal the newest Underdog promo code, good for $100 in bonus entries once you play $5 with the promo code CBSSPORTS2 in choose states.
Prime Week 10 NFL AI picks
After analyzing each sport in Week 10, the AI says the Buffalo Payments (-9.5) cowl comfortably towards the Miami Dolphins, who could also be on their method to a rebuild. Josh Allen leads the Buffalo offense, finishing 70.4% of his passes for 1,833 yards and 13 touchdowns with 4 interceptions. He has additionally rushed 55 occasions for 280 yards (5.1 common) and 7 touchdowns, together with two within the 28-21 Week 9 win over the Kansas Metropolis Chiefs.
Miami has struggled of late, shedding 4 of their final 5 video games, together with a 28-6 loss to the Baltimore Ravens on Thursday Evening Soccer on Oct. 30. Within the aftermath of the sport, the Dolphins parted methods with longtime basic supervisor Chris Grier. Even with James Prepare dinner (ankle) lacking apply on Wednesday, SportsLine AI charges the Payments as an A+ decide on the cash line and likewise predicts a 36-22 win on common. See its different Week 10 soccer predictions and soccer picks at SportsLine, and guess the Payments right here:
make Week 10 NFL picks
As well as, the AI PickBot has generated nicely over 20 highly-coveted A+ picks for Week 10. It’s good to see the AI’s NFL picks earlier than making any Week 10 NFL bets of your individual. You possibly can solely see them at SportsLine.
Who wins and covers every Week 10 NFL sport, and which A+ picks do you have to goal now? Go to SportsLine now to see the highest NFL picks towards the unfold, over-under, and on the cash line, all from the SportsLine AI that has nailed greater than 2,000 highly-rated picks because the begin of the 2023 season.
![[Inside the Newsroom] The issues we do for love…](https://www.rappler.com/tachyon/2026/02/journalism-love-feb-13-2026.jpg "[Inside the Newsroom] The issues we do for love…")
