Nasdaq, S&P 500 Open Increased to Begin Week; Novo Nordisk Plummets After Ozempic Alzheimer’s Miss

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Comfortable Monday. That is TheStreet’s Inventory Market At this time for Nov. 24, 2025. You possibly can observe the newest updates in the marketplace right here in our each day reside weblog.

The U.S. markets are actually open. The Nasdaq (+1.33%) is beginning the week on robust footing, trailed by the S&P 500 (+0.75%). In the meantime, the Russell 2000 (+0.35%) and Dow (+0.25%) are additionally up, albeit, bested by some margin.

Updates might be added right here shortly.

Weight reduction tablets have been floated as a doable therapy for all the things. Nevertheless, Alzheimer’s is outwardly not a kind of illnesses simply handled by the burgeoning GLP-1 class of medication.

Novo Nordisk (-10.4%) is plummeting this morning, dragging down shares of Eli Lilly (-1%) after its weight reduction capsule Ozempic didn’t “exhibit a statistically vital discount in Alzheimer’s illness development” in a part 3 examine.

Novo’s Government VP of Analysis and Improvement says that they pursued the examine primarily based on “vital unmet want in Alzheimer’s in addition to quite a few indicative information factors,” however the examine was largely seen as a long-shot. There are possible different indications the place the blockbuster drug could possibly be trialed to better impact, very similar to the businesses did with weight reduction.

Other than the GLP-1 names, listed below are the movers for as we speak, per MarketWatch:

Encourage Medical Methods (+18.5%) is leaping after an improve from Stifel, which bumped the corporate’s share goal to $110 amid larger reimbursements. It is joined by Ingredion (+9.8%), which has confronted adverse information in current weeks however introduced a deal to exit its stake in a three way partnership with companion Amyris. Lastly, Centene (+8.3%) is leaping amid new analyst upgrades and hopes of a brand new Republican well being care plan which is able to lengthen Obamacare subsidies for a minimum of two years.

On the opposite finish of the market, Novocure (-7.3%) seems to be falling, joined by New York Occasions Co (-5.5%), Paycom (-4.8%), and Fashionable Inc (-3.88%).

Good morning. After a tough week for U.S. equities — which noticed the Nasdaq decline 2.2% regardless of a shocking rally to finish the week — the market is ticking larger this morning. Futures are pointing to a wholesome open for the key indexes, that are up between 0.17% and 0.68%.

Regardless of the current jitters in markets, banks are placing out their guesswork for the place issues could possibly be in a 12 months’s time — and so they’re nonetheless feeling bullish, apparently. Here is only a cropping of the strangeness we’re listening to:

• Deutsche Financial institution units 2026 year-end S&P 500 goal at 8,000

• Morgan Stanley raises 12-month goal for S&P 500 to 7,800

• JPMorgan analysts forecast Brent Crude “could” decline into the $30s in 2027

Keep in mind for a second that the S&P 500 closed Friday at 6,602.99 and Brent steady contract is sitting at 62.09 this morning. These are some fascinating predictions, even when you can kind of directionally see the place they’re coming from.

That mentioned, let’s check out what is going on on as we speak:

Monday is mostly a sluggish day for earnings, particularly once you’re nearer to the tip of the season than the beginning. Here is what to anticipate, principally after the market closes:

This morning, the Dallas Fed Manufacturing Index might be out at 11:30 a.m., our solely severe report for the day. In its final displaying, it registered a -5. It will precede an exceptionally busy Tuesday, which is able to see a deluge of multinational information launched.

This story was initially reported by TheStreet on Nov 24, 2025, the place it first appeared within the Newest Enterprise & Market Information part. Add TheStreet as a Most well-liked Supply by clicking right here.