After a grueling 12 months of chemotherapy, surgical procedure, and radiation to deal with breast most cancers, Sadia Zapp was anxious — not the manageable hum that had lengthy been a part of her life, however one thing deeper, extra distracting.
“Each little ache, like my knee hurts,” she mentioned, made her fear that “that is the tip of the street for me.”
So Zapp, a 40-year-old communications director in New York, grew to become one in all tens of millions of People to begin taking an nervousness medicine lately. For her, it was the serotonin-boosting drug Lexapro.
“I adore it. It has been nice,” she mentioned. “It is actually helped me handle.”
The proportion of American adults who took nervousness drugs jumped from 11.7% in 2019 to 14.3% in 2024, with many of the improve occurring in the course of the COVID pandemic, in accordance with survey information from the Facilities for Illness Management and Prevention. That is 8 million extra individuals, bringing the entire to roughly 38 million, with sharp will increase amongst younger adults, individuals with a school diploma, and adults who determine as LGBTQ+.
Jackie Molloy for KFF Well being Information
Whilst psychiatric drugs achieve public acceptance and change into simpler to entry by telehealth appointments, the rise of a category of antidepressants known as selective serotonin reuptake inhibitors, often called SSRIs, has triggered a backlash from supporters of the “Make America Wholesome Once more” motion who argue they’re dangerous. Docs and researchers say drugs similar to Prozac, Zoloft, and Lexapro are front-line remedies for a lot of nervousness problems, together with generalized nervousness dysfunction and panic dysfunction, and are being misrepresented as addictive and broadly dangerous regardless that they have been proved secure for prolonged use.
Well being and Human Providers Secretary Robert F. Kennedy Jr. has decried broadening SSRI use. Throughout his Jan. 29 affirmation listening to, he mentioned he is aware of individuals, together with relations, who had a more durable time quitting SSRIs than individuals have quitting heroin. Extra lately, he mentioned his company is finding out a attainable hyperlink between using SSRIs and different psychiatric drugs and violent conduct like college shootings.
Meals and Drug Administration Commissioner Marty Makary has additionally steered that SSRI use amongst pregnant ladies might result in poor beginning outcomes.
SSRIs’ frequent unwanted side effects embrace upset abdomen, mind fog, and fatigue. Some SSRIs additionally can scale back libido and trigger different sexual unwanted side effects.
For many individuals, nevertheless, the unwanted side effects are gentle and tolerable and the advantages of treating continual nervousness are value it, mentioned Patrick Kelly, president of the Southern California Psychiatric Society. “The statements about SSRIs had been simply not grounded in any kind of proof or reality,” Kelly mentioned of Kennedy’s feedback.
A latest complete examine confirmed that over half of individuals with generalized nervousness dysfunction taking an SSRI noticed their nervousness signs decreased by a minimum of 50%. Uncomfortable side effects prompted about 1 in 12 to cease taking an SSRI.
“When it is being accomplished proper and whenever you’re additionally utilizing applicable remedy methods, SSRIs could be actually, actually useful,” mentioned Emily Wooden, a psychiatrist who practices in Los Angeles.
MAHA blames nervousness on poor weight loss plan, lack of train
Supporters of MAHA have partly blamed poor dietary selections and the rise of a sedentary way of life for the rise of quite a few well being issues, together with nervousness, melancholy, and different psychological well being problems. As a treatment, they’ve known as for measures similar to decreasing consumption of ultraprocessed meals, which research in latest years have linked to melancholy and nervousness, and slicing again on display time in favor of train.
Psychiatrists typically encourage a nutritious diet and train as an adjunctive remedy for nervousness and melancholy. Wooden mentioned those that can handle nervousness with out medicine also needs to take into account speak remedy. The proportion of American adults utilizing psychological well being counseling boomed from 2019 to 2024 as teletherapy grew in reputation, federal information reveals. “Nervousness problems are amongst our psychiatric problems that actually reply nicely to cognitive behavioral remedy,” she mentioned.
However medicine might help.
Research present the dangers of taking SSRIs throughout being pregnant are low for mom and youngster. In contrast, “melancholy will increase your threat for each complication for a mom and a child,” Wooden mentioned, including that latest statements by authorities officers about SSRI use throughout being pregnant are “probably resulting in actual hurt for these ladies.”
Some individuals who cease taking antidepressant medicine will expertise nausea, insomnia, or different signs, particularly in the event that they give up all of the sudden. However “the idea of habit merely doesn’t apply to those chemical compounds,” Kelly mentioned, a press release backed up by research.
Habit, although, is a chance with benzodiazepines similar to Xanax which can be typically a second line of therapy for nervousness. These managed substances may improve the danger of opioid overdose in sufferers taking each forms of medication. Throughout congressional hearings final 12 months, Kennedy additionally decried benzodiazepine overuse as an issue.
Whereas benzodiazepines are efficient for short-term use, they require monitoring and care, Wooden mentioned.
“These are actually nice meds for acute nervousness and never nice as long-term nervousness drugs, as a result of they’re habit-forming over time,” Wooden mentioned. “If you happen to’re taking them every day, you may want an increasing number of to get the identical impact, after which it’s a must to come down from them in a tapered means.”
And an rising variety of individuals are additionally often taking beta-blockers similar to propranolol for nervousness. Some individuals use beta-blockers to stop a racing coronary heart earlier than a public speech or different massive moments, regardless that they aren’t FDA-approved for treating nervousness and are prescribed “off-label.”
Beta-blockers could cause dizziness and fatigue, however they’re “nonaddictive, actually useful for bringing down the autonomic nervous system, going from combat or flight to one thing extra impartial, and actually secure,” Wooden mentioned.
Social shifts drive elevated use of tension meds
Numerous main theories might clarify why so many extra persons are taking nervousness medicine, together with elevated social media use, extra isolation, and heightened financial uncertainty, physicians and researchers say.
Plus, the medicines are comparatively straightforward to get. Many individuals get hold of SSRI and benzodiazepine prescriptions from their major care doctor. Others get hold of the drugs after a quick teletherapy appointment.
Many social media influencers discuss their psychological well being struggles, easing some stigma amongst younger individuals and inspiring them to get assist. A couple of third of teenagers in a latest examine mentioned they get psychological well being info through social media.
Nonetheless, elevated entry to nervousness medicine generally is a downside when mixed with a development of self-diagnosis primarily based on social media traits. A Google seek for “purchase Xanax on-line” results in sponsored guarantees of same-day therapy, although fine-print disclaimers make clear {that a} prescription will not be assured.
“I believe elevated entry is nice, however that is not the identical factor as, you already know, ordering Xanax on-line,” Kelly mentioned.
Younger adults are largely driving a rise in nervousness medicine use. The proportion of People ages 18 to 34 taking nervousness medicine rose from 8.8% in 2019 — the primary 12 months such survey information grew to become obtainable — to 14.6% in 2024. In contrast, the speed did not change a lot amongst adults 65 and older, CDC information reveals.
The pandemic and COVID lockdowns drastically elevated stress amongst many American adults, significantly younger adults.
And information reveals extra ladies than males take nervousness medicine. Jason Schnittker, a division chair and professor of sociology on the College of Pennsylvania, mentioned that is as a result of they’re extra prone to want them. They’re additionally likelier than males to report once they really feel anxious, and medical doctors are “inclined or see nervousness extra readily of their feminine sufferers than their male sufferers,” Schnittker added.
Broader traits may be at work. Schnittker mentioned research have proven nervousness rising extra prevalent amongst ensuing generations for a lot of the twentieth and twenty first centuries. Schnittker, creator of “Unnerved: Nervousness, Social Change, and the Transformation of Trendy Psychological Well being,” mentioned rising earnings inequality could possibly be partly responsible, with individuals feeling stress over enhancing their financial standing. Social and non secular actions have been changed by extra isolation. And other people have change into extra suspicious of others, creating a way of unease round strangers.
For Zapp, the most cancers survivor, it took a couple of months on Lexapro earlier than she began seeing clear outcomes. When she did, she mentioned, it felt like her thoughts was much less noisy, making it simpler to focus. She additionally underwent speak remedy, however now her continual nervousness is stabilized on medicine alone.
“It undoubtedly helped me get again to my day-to-day in a means that was productive and never simply riddled with my anxieties all through the day,” she mentioned.
KFF Well being Information’ Holly Hacker, Maia Rosenfeld, and Lydia Zuraw contributed to this report.
KFF Well being Information is a nationwide newsroom that produces in-depth journalism about well being points and is likely one of the core working packages at KFF — the impartial supply for well being coverage analysis, polling, and journalism.
