Cardinals vs. Seahawks prediction, odds, time: 2025 NFL Week 4 Thursday Night time Soccer picks from confirmed mannequin

An NFC West conflict kicks off NFL Week 4 on ‘Thursday Night time Soccer’ because the Seattle Seahawks go to the Arizona Cardinals. Each groups are 2-1, with the Seahawks coming off back-to-back victories. Seattle rolled over the Saints 44-13 in Week 3 after one other double-digit victory over Pittsburgh in Week 2. In the meantime, Arizona suffered its first lack of the 12 months in a 16-15 defeat to the 49ers on Sunday. This rivalry hasn’t been a lot of that in current conferences because the Seahawks have taken every of the final seven matchups.

Kickoff is at 8:15 p.m. ET from State Farm Stadium in Glendale, Ariz. The newest Seahawks vs. Cardinals odds have Seattle because the 1.5-point favourite, whereas the over/below for complete factors is 43.5. Earlier than making any Cardinals vs. Seahawks picks, make sure to see what the SportsLine projection mannequin has to say. 

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The mannequin, which simulates each NFL sport 10,000 occasions, is up properly over $7,000 for $100 gamers on top-rated NFL picks since its inception. The mannequin is on a scorching 39-19 run on top-rated picks relationship again to 2024. Anyone following its NFL betting picks at sportsbooks and on betting websites may have seen robust returns.

Now, the mannequin has zeroed in on Seattle vs. Arizona. You may head to SportsLine now to see its picks. Listed below are a number of NFL odds and betting traces for Cardinals vs. Seahawks:

Why the Seahawks can cowl

Seattle’s using a seven-game win streak versus Arizona, with 5 of these victories coming by double-digits. None of these wins got here with Sam Darnold below heart, however the well-traveled quarterback has been among the many greatest versus the unfold in current seasons. Darnold is 17-9-1 ATS because the begin of 2022, with that 65% cowl price the second-best amongst quarterbacks over this span. Darnold’s over/below for passing yardage is 223.5. 

Since Mike Macdonald grew to become Seattle’s head coach in 2024, Seattle is 5-1 ATS as a highway underdog. This 12 months’s squad is excelling on either side of the ball, rating within the prime 5 in each scoring offense and scoring protection. Seattle is the one NFL workforce that hasn’t allowed a dashing landing this 12 months, making it an much more arduous activity for Arizona to seek out success on the bottom because the workforce misplaced 1,000-yard rusher James Conner (leg) for the season on Sunday. See which workforce to again at SportsLine. 

Why the Cardinals can cowl

Regardless of coming off a loss to San Francisco, Arizona did handle to cowl within the sport and is now 10-4 ATS over its final 14 video games. Head coach Jonathan Gannon continues to work wonders on the defensive aspect of the ball because the Playing cards ranked thirty first in scoring protection in 2023, then fifteenth in 2024 and are actually fifth this season. The Cardinals make an opponent one-dimensional on offense after which carry out their greatest in clutch conditions as Arizona ranks top-five in dashing protection, third-down protection and redzone protection.

Whereas Conner’s harm is an emotional setback for Arizona, it does permit the workforce to make the most of second-year again, Trey Benson, extra. His 6.0 yards per carry rank second within the NFL, whereas Kyler Murray’s 5.4 yards per rush are seventh-best. Moreover, simply 4 groups have a greater turnover differential than the Playing cards, which the mannequin has taken under consideration. SportsLine’s projections forecast Arizona’s protection to each rack up extra sacks than Seattle’s and to pressure extra turnovers on Thursday. See which workforce to again at SportsLine. 

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Learn how to make Cardinals vs. Seahawks picks

For the NFL Week 4 Thursday Night time Soccer sport of Seahawks vs. Cardinals, the mannequin is leaning Over the entire, and likewise says one aspect of the unfold is the higher worth. See what it’s at SportsLine.

Who wins Cardinals vs. Seahawks, and which aspect of the unfold is the higher worth? Go to SportsLine now to see which aspect of the Seahawks vs. Cardinals unfold it is advisable to leap, all from the mannequin that’s 39-19 on top-rated picks since 2024, and discover out.