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Duke vs. Louisville prediction, odds, time, line: 2026 faculty basketball picks from confirmed mannequin

Madisony
Last updated: January 27, 2026 10:33 am
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Duke vs. Louisville prediction, odds, time, line: 2026 faculty basketball picks from confirmed mannequin
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The No. 23 Louisville Cardinals tackle the fifth-ranked Duke Blue Devils in a key ACC matchup on Monday night time. Louisville is coming off an 85-71 win over Virginia Tech on Saturday, whereas Duke downed Wake Forest 90-69 that very same day. The Cardinals (14-5, 4-3 ACC), who’re tied for sixth within the convention, are 2-3 on the highway this season. The Blue Devils (18-1, 7-0 ACC), who’re 6-1 in opposition to ranked opponents, are 9-0 on their house court docket.

Tipoff from Cameron Indoor Stadium in Durham, N.C., is ready for 7 p.m. ET. Duke is an 8.5-point favourite within the newest Louisville vs. Duke odds from DraftKings Sportsbook, whereas the over/underneath for complete factors scored is 157.5. Earlier than making any Duke vs. Louisville picks, try the lads’s faculty basketball predictions and betting recommendation from the SportsLine Projection Mannequin.

New customers can goal the DraftKings promo code, which presents $300 in bonus bets in case your $5+ wager wins:

The SportsLine Projection Mannequin simulates each faculty basketball sport 10,000 occasions and it enters Week 13 on a scorching 10-1 run on its top-rated over/underneath faculty basketball picks relationship again to final season, and it’s on a 6-0 roll on faculty basketball facet picks. Anybody following its faculty basketball betting recommendation at sportsbooks and on betting apps might have seen sturdy returns.

Now, the mannequin has simulated Louisville vs. Duke 10,000 occasions and simply revealed its coveted males’s faculty basketball picks and betting predictions. You’ll be able to head to SportsLine now to see the mannequin’s picks. Listed below are a number of males’s faculty basketball odds and males’s faculty basketball betting traces for Duke vs. Louisville:

Louisville vs. Duke unfold:    

Duke -8.5 at DraftKings Sportsbook

Louisville vs. Duke over/underneath:    

157.5 factors

Louisville vs. Duke cash line:    

Duke -461, Louisville +350

Louisville vs. Duke picks:    

See picks at SportsLine

Louisville vs. Duke streaming:

Fubo (Attempt totally free)  

New customers can try the newest bet365 bonus code to get $200 in bonus bets after inserting a $5 wager:

The best way to make Louisville vs. Duke picks

SportsLine’s mannequin is going Below on the entire (157.5 factors). The Below has hit in every of the final 4 head-to-head matchups between the faculties. The Below has additionally hit in 5 of the final six Louisville video games, and in two of the final three Duke video games. The Cardinals are 4-6 in opposition to the unfold of their final 10 video games, whereas the Blue Devils are 5-5 ATS of their final 10.

The mannequin tasks the Cardinals to have 4 gamers register 10.7 factors or extra, together with Ryan Conwell’s projected 17.7 factors. The Blue Devils, in the meantime, are projected to have 4 gamers rating 10 or extra factors, led by Cameron Boozer, who’s projected to attain 22.4 factors. The mannequin tasks a mixed complete of 157 factors because the Below clears in effectively over 50% of simulations.

The mannequin additionally says one facet of the unfold hits greater than 50% of the time. You’ll be able to solely see that decide at SportsLine.

So who wins Duke vs. Louisville, and which facet of the unfold hits greater than 50% of the time? Go to SportsLine now to see which facet of the Louisville vs. Duke unfold to again, all from the superior mannequin that has simulated this sport 10,000 occasions, and discover out.



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