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Indiana vs. Ohio State prediction, odds, line: 2025 Massive Ten Championship Sport picks from confirmed mannequin

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Last updated: December 6, 2025 6:13 am
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Indiana vs. Ohio State prediction, odds, line: 2025 Massive Ten Championship Sport picks from confirmed mannequin
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Contents
Why Ohio State can cowlWhy Indiana can cowl Find out how to make Ohio State vs. Indiana picks

The highest two groups within the nation meet within the 2025 Massive Ten Championship Sport when the second-ranked Indiana Hoosiers battle the top-ranked Ohio State Buckeyes on Saturday. Indiana is coming off a 56-3 win at Purdue on Nov. 28, whereas Ohio State defeated Michigan 27-9 on Nov. 29. The Hoosiers (12-0, 9-0 Massive Ten), who’re showing of their first Massive Ten title recreation, are 2-0 towards ranked opponents this season. The Buckeyes (12-0, 9-0 Massive Ten), the defending nationwide champions, are enjoying of their seventh convention championship recreation.

Kickoff from Lucas Oil Stadium in Indianapolis is at 8 p.m. ET. Ohio State leads the all-time sequence 82-12-5, together with a 38-14 win in 2024. The Buckeyes are 4-point favorites within the newest Ohio State vs. Indiana odds, whereas the over/below for whole factors scored is 47.5 by way of SportsLine consensus. Earlier than making any Indiana vs. Ohio State picks, try the school soccer predictions from the SportsLine Projection Mannequin. 

New customers can goal the DraftKings promo code, which gives $200 in bonus bets in case your $5+ wager wins:

The mannequin simulates each FBS recreation 10,000 instances, and it’s worthwhile on its top-rated money-line and over/below picks for the reason that starting of the 2024 season. Anyone following these faculty soccer betting picks at sportsbooks and on betting websites might have seen sturdy returns.

Now, the mannequin has set its sights on Indiana vs. Ohio State. You possibly can go to SportsLine now to see the picks. Listed below are the FBS faculty soccer odds and traits for Ohio State vs. Indiana:

Indiana vs. Ohio State unfold

Ohio State -4 at DraftKings Sportsbook

Indiana vs. Ohio State over/below

47.5 factors

Indiana vs. Ohio State cash line 

Indiana +161, Ohio State -139

Indiana vs. Ohio State picks

See picks at SportsLine

Indiana vs. Ohio State streaming 

Fubo (Strive free of charge)  

New customers may also try the newest FanDuel promo code and get $150 in bonus bets at FanDuel in case your $5 wager wins. 

Why Ohio State can cowl

Sophomore quarterback and Heisman quarterbaack Julian Sayin guides the Buckeyes’ offense. In 12 video games, he has accomplished 78.9% of his passes for 3,065 yards and 30 touchdowns with simply 5 interceptions. In final week’s win at Michigan, he accomplished 19 of 26 passes for 233 yards and three touchdowns with one interception. He accomplished 36 of 42 passes for 393 yards and 4 touchdowns in a 34-0 win over the Wisconsin Badgers on Oct. 18.

Powering the bottom assault is freshman operating again Bo Jackson. In 11 video games, he has rushed 151 instances for 952 yards (6.3 common) and 5 touchdowns. He has rushed for 100 or extra yards in three consecutive video games, and in six video games general. He additionally has 17 receptions for 187 yards and one landing. In final week’s win over the Wolverines, he carried 22 instances for 117 yards. See which group to again at SportsLine.

Why Indiana can cowl 

Junior quarterback Fernando Mendoza, additionally a Heisman candidate, leads the Hoosiers’ assault. In 12 video games, he has accomplished 211 of 293 passes (72%) for two,758 yards and 32 touchdowns with 5 interceptions. He has additionally rushed 64 instances for 243 yards (3.8 common) and 6 touchdowns. In a 31-7 win over Wisconsin on Nov. 15, he accomplished 22 of 24 passes for 299 yards and 4 touchdowns.

The Indiana speeding assault is led by senior operating again Roman Hemby. In 12 video games, he has rushed 163 instances for 866 yards (12.7 common) and one landing. In final week’s win at Purdue, he carried 12 instances for 152 yards (12.7 common) and one landing. He carried 17 instances for 81 yards (4.8 common) and two touchdowns in a 56-6 win over UCLA on Oct. 25. See which group to again at SportsLine.

Find out how to make Ohio State vs. Indiana picks

SportsLine’s mannequin goes Over on the whole. It additionally says one aspect of the unfold hits over 50% of the time. You possibly can see the mannequin’s choose at SportsLine.  

So who wins Ohio State vs. Indiana, and which aspect of the unfold hits greater than 50% of the time? Go to SportsLine now to see which aspect of the Indiana vs. Ohio State unfold to leap on, all from the superior mannequin that is up on its top-ranked money-line and whole picks, and discover out.



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