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Northwestern vs. USC odds, line, picks, predictions, finest bets from confirmed mannequin

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Last updated: November 7, 2025 12:25 pm
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Northwestern vs. USC odds, line, picks, predictions, finest bets from confirmed mannequin
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Contents
Why USC can cowlWhy Northwestern can cowlThe way to make USC vs. Northwestern picks

The Nineteenth-ranked USC Trojans will look to remain within the Massive Ten title chase after they battle the Northwestern Wildcats on Friday night time. USC is coming off a 21-17 win at Nebraska this previous week, whereas Northwestern dropped a 28-21 choice at Nebraska on Oct. 25. The Wildcats (5-3, 3-2 Massive Ten), who’re tied for eighth within the convention, are 1-2 on the highway this season. The Trojans (6-2, 4-1 Massive Ten), who’re tied for fourth, are 4-0 on their house subject in 2025. USC operating again Waymond Jordan (ankle) is uncertain.

Kickoff from the Los Angeles Memorial Coliseum is at 9 p.m. ET. USC leads the all-time sequence 5-0. The groups final met within the 1996 Rose Bowl, which the Trojans gained 41-32. The Trojans are 14.5-point favorites within the newest Northwestern vs. USC odds, whereas the over/below for complete factors scored is 50.5 through SportsLine consensus. Earlier than making any USC vs. Northwestern picks, try the faculty soccer predictions from the SportsLine Projection Mannequin. 

New customers can goal the DraftKings promo code, which provides $300 in bonus bets in case your wager wins + 3 months of NBA League Move:

The mannequin simulates each FBS recreation 10,000 instances. Since its inception, it has generated a betting revenue of over $2,000 for $100 gamers on its top-rated school unfold soccer picks. Anyone following its school soccer betting picks at sportsbooks and on betting websites may have seen robust returns.

Now, the mannequin has set its sights on Northwestern vs. USC. You’ll be able to go to SportsLine now to see the picks. Listed here are the FBS school soccer odds and tendencies for USC vs. Northwestern:

Northwestern vs. USC unfold

USC -14.5 at DraftKings Sportsbook

Northwestern vs. USC over/below

40.5 factors

Northwestern vs. USC cash line 

USC -667, Northwestern +476

Northwestern vs. USC picks

See picks at SportsLine

Northwestern vs. USC streaming 

Fubo (Strive without spending a dime)  

Why USC can cowl

Junior quarterback Jayden Maiava powers the Trojans’ offense. In eight video games, he has accomplished 154 of 236 passes for two,315 yards and 15 touchdowns with 5 interceptions. He has additionally rushed 34 instances for 103 yards and 5 scores. In a 45-31 win over Michigan State on Sept. 20, he accomplished 20 of 26 passes for 234 yards and three touchdowns. He additionally carried 4 instances for 31 yards and two touchdowns.

With Jordan doubtless out, the dashing assault will likely be spearheaded by freshman operating again King Miller. He’s coming off a stable effort within the win over Nebraska. In that recreation, he carried 18 instances for 129 yards and one landing. He had 18 carries for 158 yards and a rating in a 31-13 win over Michigan on Oct. 11. In seven video games this season, he has carried 65 instances for 509 yards (7.8 common) and 4 touchdowns. See which group to again at SportsLine. 

Why Northwestern can cowl

Serving to lead the Wildcats’ offense is senior quarterback Preston Stone. The switch from SMU is in his first season with this system. In eight video games, he has accomplished 126 of 216 passes (58.3%) for 1,372 yards and 10 touchdowns with 9 interceptions. In a 22-21 win over Penn State on Oct. 11, he accomplished 17 of 26 passes for 163 yards and one landing.

Sophomore operating again Caleb Komolafe additionally offers the offense a lift. In eight video games, he has carried 124 instances for 608 yards (4.9 common) and 7 touchdowns. Within the loss at Nebraska, he carried 17 instances for 125 yards and two touchdowns. He had 27 carries for 119 yards and one rating in a 17-14 win over UCLA. See which group to again at SportsLine.

New customers may also try the newest FanDuel promo code and get $150 in bonus bets at FanDuel in case your $5 wager wins. 

The way to make USC vs. Northwestern picks

SportsLine’s mannequin goes Over on the overall, projecting 55 mixed factors. It additionally says one facet of the unfold hits in properly over 50% of simulations. You’ll be able to solely get the choose at SportsLine. 

So who wins USC vs. Northwestern, and which facet of the unfold hits in properly over 50% of the time? Go to SportsLine now to see which facet of the Northwestern vs. USC unfold to leap on, all from the superior mannequin that completed up over $2,000 on its FBS school soccer picks since its inception, and discover out.



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