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Sports

Prisco’s NFL picks, Week 6: Chiefs win shootout vs. Lions, Dolphins upset Chargers

Madisony
Last updated: October 8, 2025 11:02 am
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Prisco’s NFL picks, Week 6: Chiefs win shootout vs. Lions, Dolphins upset Chargers
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Contents
Tennessee Titans at Las Vegas Raiders (-4.5)Chicago Bears (+4.5) at Washington Commanders

After two good weeks, it was again to common for me final week with my NFL picks.

The excellent news is that it wasn’t a shedding week. I went 8-6 straight up and 7-7 in opposition to the unfold.

That is a cooler the way in which I had been going.

My season data at the moment are 57-20-1 straight up and 43-35 ATS. Anytime you could be over .500 ATS after 5 weeks, that counts as a great begin to the 12 months.

Just like the groups within the NFL, now could be go time. That is when contenders emerge and pretenders begin to fade away.

I plan on being a contender, so right here we go.

Guess NFL Week 6 video games and NFL odds at DraftKings, the place new customers get $200 in bonus bets with a successful $5 wager. Click on right here to get began:

Thursday, 8:15 p.m. on Prime Video

The Eagles misplaced for the primary time final week and have not seemed that spectacular in attending to 4-1. They should run Saquon Barkley extra and they’ll on this one in opposition to his former workforce. The Giants turned the ball over an excessive amount of in shedding to the Saints final week and I feel Jaxson Dart may have some troubles in opposition to the Eagles protection. Eagles massive.  

Choose: Eagles 29, Giants 17 | Odds through BetMGM

Sunday, 9:30 a.m. on NFL Community (Stream: Fubo — strive free of charge)

The Jets are a catastrophe proper now at 0-5, displaying nothing on protection. The Broncos are using excessive after beating the Eagles final week. Bo Nix performed higher within the second half of that sport than he did all 12 months, which is able to carry over right here. The Jets do not sort out and the Broncos will make the most of it. 

Choose: Broncos 26, Jets 14 | Odds through BetMGM

Sunday, 1 p.m. on Fox (Stream: Fubo — strive free of charge)

The Colts impressed in beating the Raiders final week, whereas Arizona is coming off the kind of loss to the Titans that may demoralize a workforce. This might be an actual problem for the Arizona protection and I feel Daniel Jones will proceed to play properly. Colts take it. 

Choose: Colts 27, Cardinals 24 | Odds through Caesars Sportsbook

Sunday, 1 p.m. on CBS (Stream on Paramount+)

The Steelers are coming off a bye, whereas the Browns are coming off a loss to the Vikings in London final week. Dillon Gabriel made his first begin at quarterback in that sport and dealt with himself properly, however did not roll up massive numbers as they performed it secure. The Steelers have performed properly in attending to 3-1, particularly Aaron Rodgers. However this Browns protection will preserve them within the sport. It is shut. 

Choose: Steelers 21, Browns 18 | Odds through FanDuel Sportsbook, the place new customers get $300 in bonus bets with a successful $5 wager:

Sunday, 1 p.m. on Fox (Stream: Fubo — strive free of charge)

The Cowboys are enjoying consecutive highway video games, however they’re rolling on offense with Dak Prescott. The Panthers got here again to beat Miami final week, however slowing Prescott might be an enormous problem. Search for the Cowboys offense to proceed to roll as their protection continues to enhance. Dallas wins it. 

Choose: Cowboys 30, Panthers 21 | Odds through DraftKings Sportsbook

Sunday, 1 p.m. on CBS (Stream on Paramount+)

It is a lengthy journey for a beat-up Chargers workforce that did not play properly within the second half final week of their loss to the Commanders. The Dolphins are coming off a nasty loss to the Panthers. Their protection has struggled to cease the run, however the Chargers have harm points on their line and within the backfield. The Dolphins will win this one behind a great sport by Tua Tagovailoa. 

Choose: Dolphins 27, Chargers 26 | Odds through Caesars Sportsbook

Sunday, 1 p.m. on Fox (Stream: Fubo — strive free of charge)

The Ravens are a multitude, whereas the Rams are coming off a nasty loss to the 49ers at dwelling. The Ravens will probably be with out Lamar Jackson once more, and the banged-up protection cannot cease anyone. The Rams protection did not play properly in opposition to the 49ers, however will right here. Rams take it.

Choose: Rams 31, Ravens 17 | Odds through BetMGM

Sunday, 1 p.m. on CBS (Stream on Paramount+)

The Patriots are using excessive after beating the Payments on Sunday night time, however this might be a troublesome sport coming off that massive victory. The Saints beat the Giants final week as Spencer Rattler and the protection performed massive. This might be a problem for the Patriots and Drake Maye. It is shut, however Maye will win it late. 

Choose: Patriots 22, Saints 21 | Odds through Caesars Sportsbook, the place new customers get 20 100% revenue boosts with the code CBS20X:

Sunday, 1 p.m. on Fox (Stream: Fubo — strive free of charge)

It is a lengthy journey for Seattle, however the Jaguars are enjoying on a brief week, which evens it out. Seattle did not look good final week on protection. However this has the look of a shootout to me. Search for the Jaguars to proceed to roll as Trevor Lawrence wins a wild one in opposition to Sam Darnold.

Choose: Jaguars 33, Seahawks 30 | Odds through BetMGM

Tennessee Titans at Las Vegas Raiders (-4.5)

Sunday, 4:05 p.m. on Fox (Stream: Fubo — strive free of charge)

The Titans are enjoying consecutive highway video games after successful in miraculous style final week at Arizona. The Raiders have been blown out by the Colts final week in sport through which they seemed lifeless. Geno Smith hasn’t performed properly, however I feel he’ll play higher right here. The Raiders win it.

Choose: Raiders 27, Titans 17 | Odds through DraftKings Sportsbook

Sunday, 4:25 p.m. on CBS (Stream on Paramount+)

The Bengals have main offensive points with Jake Browning enjoying quarterback, which is why they traded for Joe Flacco. Whoever performs quarterback is on the highway in opposition to a great Packers protection coming off a bye. This might be ugly for the Bengals once more as Inexperienced Bay wins it, due to a protection that did not play properly the final trip. 

Choose: Packers 31, Bengals 17 | Odds through Caesars Sportsbook

Sunday, 4:25 p.m. on CBS (Stream on Paramount+)

The 49ers are rested after enjoying final Thursday, which is able to assist the injured. They upset the Rams, whereas Tampa Bay beat Seattle behind Baker Mayfield final week. Mac Jones performed properly for the 49ers, however Mayfield and the Bucs are on a scorching streak. They are going to preserve it rolling. 

Choose: Buccaneers 30, 49ers 20 | Odds through FanDuel Sportsbook

Sunday, 8:20 p.m. on NBC (Stream: Fubo — strive free of charge)

The Chiefs are on a brief week off a troublesome loss to the Jaguars on Monday night time. However they face a banged-up Lions workforce. The Chiefs are in desperation mode, and I feel that may present right here. The Chiefs will win a high-scoring sport, making the most of the injured Lions protection. Patrick Mahomes will win it late. 

Choose: Chiefs 34, Lions 30 | Odds through FanDuel Sportsbook

Monday, 7:15 p.m. ET on ESPN (Stream: Fubo — strive free of charge)

The Payments are coming off their first loss Sunday night time, whereas the Falcons are coming off a bye. The Falcons will current a troublesome problem for the Payments protection, however I feel this sport might be about Josh Allen. He’ll begin to hit photographs down the sector within the passing sport, which hasn’t occurred a lot this season, because the Payments win it. 

Choose: Payments 33, Falcons 27 | Odds through DraftKings Sportsbook

Chicago Bears (+4.5) at Washington Commanders

Monday, 8:15 p.m. ET on ABC (Stream: Fubo — strive free of charge)

This sport matches Caleb Williams vs. Jayden Daniels, the 2 prime picks within the 2024 NFL Draft. They met final 12 months in a sport received on a Hail Mary by Daniels. The Bears are coming off a bye and two straight victories, however this sport might be received by Daniels outplaying Williams. Commanders take it. 

Choose: Commanders 31, Bears 27 | Odds through DraftKings Sportsbook



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Reading: Prisco’s NFL picks, Week 6: Chiefs win shootout vs. Lions, Dolphins upset Chargers
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