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Final minute finest bets for NFL Week 6: Again these two street groups, plus why Steelers will cowl vs. Browns

Madisony
Last updated: October 12, 2025 10:43 am
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Final minute finest bets for NFL Week 6: Again these two street groups, plus why Steelers will cowl vs. Browns
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We’ve got ourselves one other prolonged day of soccer in entrance of us. As soon as once more, the motion will get began a bit sooner than ordinary with the Denver Broncos and New York Jets kicking issues off from London, which implies we get some morning soccer to pair with our espresso. 

From there, issues solely ramp up. Joe Flacco is primed to make his debut for the Cincinnati Bengals after being acquired in a commerce with the Browns earlier this week. In the meantime, Baltimore seems to keep away from a 1-5 begin with out Lamar Jackson (hamstring), and the Chiefs will look to claw again to .500 once they host the Lions in prime time. 

This slate guarantees to ship on the leisure entrance, however what about on the playing aspect of issues? That is the place we are available in. Under, yow will discover our 5 finest bets for the Week 6 slate and our picks for the remaining video games, so you might be properly located for Sunday. 

Groups on the bye in Week 6: Minnesota Vikings and Houston Texans

NFL odds by way of DraftKings (until in any other case famous). Wager NFL Week 5 video games and NFL odds at DraftKings, the place new customers get $200 in bonus bets with a profitable $5 wager.

  • Sunday, 1 p.m. (Fox | Fubo, strive free of charge)

We rode with the Jaguars in Week 5, and now we will fade them per week later. Whereas Jacksonville is among the extra shocking tales of the 2025 season up to now with a 4-1 file, I nonetheless have loads of questions on them, notably surrounding Trevor Lawrence. He is twenty fourth amongst 33 certified quarterbacks this season in EPA per dropback, and largely did his injury on Monday evening along with his legs. The passing left little to be desired outdoors of a few late throws to drag off the upset. The Jags are one of many high speeding offenses within the NFL, however that performs right into a key energy of the Seahawks. Seattle is giving up 3.3 yards per carry this season, which is second-best within the NFL. If that continues they usually plug up the working lanes for Jacksonville, Lawrence’s passing deficiencies could possibly be uncovered. 

Additionally, let’s not ignore the large season that Sam Darnold is placing collectively for the Seahawks. Remarkably, his completion share and passer ranking are even higher than what he produced final season with the Vikings. I feel he leads Seattle into Duval County and leaves with an outright win. 

Projected rating: Seahawks 27, Jaguars 23
The choose:
Seahawks -1.5

  • Sunday, 8:20 p.m. (NBC | Fubo, strive free of charge)

The Chiefs will in all probability determine it out by the point the common season involves an finish and can once more appear to be a Tremendous Bowl contender, however I do not see it proper now. They’re unable to hold with even fringe playoff contenders, with their two victories on the yr coming in opposition to the New York Giants and an injury-filled Baltimore Ravens squad. When the video games are shut, they’ve fallen flat, proudly owning a 0-3 file in one-score video games this season. With this unfold sitting at Chiefs -2.5, I feel we’ll see extra of the identical. I’ve a tough time imagining this present model of the Chiefs offense maintaining with the Lions, who’re averaging 34.8 factors per recreation (most within the NFL). Dan Campbell’s staff comes into Arrowhead Stadium with a 10-1 file on the street courting again to the beginning of final season. This could possibly be one other stellar exhibiting from Detroit’s backfield duo of David Montgomery and Jahmyr Gibbs as they sq. off in opposition to a Chiefs run protection that’s giving up 4.8 yards per carry (tied for fifth-highest within the NFL).

Projected rating: Lions 30, Chiefs 23
The choose: 
Lions +2.5

  • Monday, 7:15 p.m. (ESPN | Fubo, strive free of charge)

Buffalo received in its personal method in opposition to the Patriots on Sunday evening, turning the ball over thrice and committing 11 penalties. I am unsure that occurs two weeks in a row. The Payments have additionally responded properly following defeats, as they’re 4-1 each straight up and in opposition to the unfold of their final 5 video games after a loss. Buffalo nonetheless is averaging 30.6 factors per recreation and 395.8 whole yards per recreation this season, which rank third within the NFL. Regardless of the top-tier weapons at his disposal, I nonetheless have my doubts about Michael Penix Jr. and his capacity to go toe to toe with Josh Allen. 

Projected rating: Payments 33, Falcons 24
The choose: 
Payments -4.5

Prisco’s Week 6 NFL picks: Determined Chiefs win shootout vs. Lions, Chargers upset by Dolphins

Pete Prisco

Prisco's Week 6 NFL picks: Desperate Chiefs win shootout vs. Lions, Chargers upset by Dolphins

  • Sunday, 9:30 a.m. (NFL Community | Fubo, strive free of charge)

I have been excessive on Denver courting to the offseason, so I am delighted that they’re lastly beginning to appear to be themselves. They’re going to look to hold the momentum from their comeback win over the Eagles in Week 5 throughout the pond to London, the place they are going to tackle the New York Jets. This ought to be a lopsided matchup with New York nonetheless winless in 2025. 

One of many extra shocking parts of the Jets poor begin to the season is that they’ve but to file a single turnover, which is blasphemous for an Aaron Glenn-led staff. If that continues, Bo Nix and the Broncos offense should not have any drawback stepping into the tip zone no less than thrice. In the event that they do, that will virtually mechanically safe them the win. In his profession, Justin Fields is 0-26 when his opponent scores 21 or extra factors. For reference, Denver is averaging 23.4 factors per recreation.

In the meantime, favorites of seven or extra factors are 8-2 ATS all time in worldwide video games, in order that’s one other feather in our cap right here.    

Projected rating: Broncos 27, Jets 17
The choose: 
Broncos -7.5

We speak rather a lot about how Mike Tomlin has by no means had a shedding season as coach of the Pittsburgh Steelers. That is definitely spectacular, however as we take a look at this upcoming matchup in opposition to the Cleveland Browns, we’re highlighting one other Tomlin-specific stat. The coach is 26-6 straight up in his profession in opposition to rookie quarterbacks. That is the second-best file by a coach with no less than 15 video games since 1970. Historical past tells us he should not have any drawback diluting Dillon Gabriel’s effectiveness on this recreation, and Pittsburgh’s 10 takeaways this season (second-most within the NFL) solely emboldens us to put the factors on this spot. Do not look now, however T.J. Watt can also be beginning to warmth up with three sacks within the final two video games. That is even worse information for Gabriel. 

Projected rating: Steelers 24, Browns 16
The choose: 
Steelers -5.5

Odds by way of BetMGM, the place you possibly can rise up to $1,500 again in bonus bets in case your first soccer wager loses.

Remainder of the bunch

Cardinals at Colts
Projected rating: Colts 30, Cardinals 21
The choose: Colts -7

Chargers at Dolphins
Projected rating: Chargers 27, Dolphins 20
The choose: Chargers -4.5

Patriots at Saints
Projected rating: Patriots 24, Saints 23
The choose: Saints +3.5

Cowboys at Panthers
Projected rating: Cowboys 33, Panthers 23
The choose: Cowboys -3

Rams at Ravens
Projected rating: Rams 30, Ravens 20
The choose: Rams -7

Titans at Raiders
Projected rating: Raiders 24, Titans 20
The choose: Titans +4.5

Bengals at Packers
Projected rating: Packers 30, Bengals 20
The choose: Bengals +14.5

49ers at Buccaneers
Projected rating: Buccaneers 23, 49ers 21
The choose: 49ers +3.5

Bears at Commanders (Monday)
Projected rating: Commanders 28, Bears 23
The choose: Commanders -4.5



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