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Seahawks vs. 49ers prediction, odds, time, date, line: NFL Week 18 Saturday picks by confirmed mannequin

Madisony
Last updated: January 3, 2026 3:38 am
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Seahawks vs. 49ers prediction, odds, time, date, line: NFL Week 18 Saturday picks by confirmed mannequin
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Why the Seahawks can cowlWhy the 49ers can cowlThe right way to make Seahawks vs. 49ers picks

The highest seed within the NFC will probably be up for grabs when the Seattle Seahawks battle the San Francisco 49ers in a key NFC West matchup on Saturday evening. Seattle is coming off a 28-10 win at Carolina on Sunday, whereas San Francisco outlasted Chicago 42-38. The Seahawks (13-3), who lead the NFC West, have received six in a row. The 49ers (12-4), who’re second within the division, have additionally received six straight and are 9-2 throughout the convention. Receiver Ricky Pearsall (knee, ankle) is questionable for the Niners. 

Kickoff from Levi’s Stadium in Santa Clara, Calif., is about for 8 p.m. ET. The Seahawks lead the all-time sequence 31-24, however San Francisco has received seven of the previous eight conferences. Seattle is the two.5-point favourite within the newest 49ers vs. Seahawks odds, whereas the over/beneath for complete factors scored is 47.5 by way of DraftKings Sportsbook. Earlier than making any Seahawks vs. 49ers picks, take a look at the NFL predictions from the SportsLine Projection Mannequin. 

The mannequin, which simulates each NFL recreation 10,000 instances, is up properly over $7,000 for $100 gamers on top-rated NFL picks since its inception. The mannequin enters Week 18 on a 53-37 run on top-rated picks courting again to 2024. Anyone following its NFL betting picks at sportsbooks and on betting websites may have seen robust returns.

Now, the mannequin has set its sights on Seahawks vs. 49ers. You may go to SportsLine now to see the picks. Listed here are the NFL odds and developments for 49ers vs. Seahawks:

Seahawks vs. 49ers unfold

Seattle -2.5 at DraftKings Sportsbook

Seahawks vs. 49ers over/beneath

47.5 factors

Seahawks vs. 49ers cash line 

Seattle -138, San Francisco +117

Seahawks vs. 49ers picks

See picks at SportsLine

Seahawks vs. 49ers streaming 

Fubo (Strive totally free)   

Why the Seahawks can cowl

Veteran quarterback Sam Darnold helps energy the Seattle offense. He has accomplished 67.2% of his passes for 3,850 yards and 25 touchdowns with 14 interceptions and a 99.2 score. In a 38-37 extra time win over the Los Angeles Rams on Dec. 18, he accomplished 22 of 34 passes for 270 yards and two touchdowns with two interceptions. In a 38-14 win at Washington on Nov. 2, he accomplished 21 of 24 passes for 330 yards and 4 touchdowns with one decide.

His high goal is third-year veteran huge receiver Jaxon Smith-Njigba. In 16 video games, he has 113 receptions for 1,709 yards and 10 touchdowns. He has 27 explosive performs of 20 yards or extra, together with a protracted of 63, with 505 yards after the catch and 74 first-down conversions. Within the win over Carolina, he caught 9 passes for 72 yards, together with a protracted of 18. See which staff to again at SportsLine. 

Why the 49ers can cowl

Quarterback Brock Purdy has been stable since getting back from harm. In eight video games this season, he has accomplished 69.3% of his passes for two,040 yards and 20 touchdowns with 9 interceptions and a 104.2 score. He has additionally carried 31 instances for 126 yards and three touchdowns. Within the win over Chicago, he accomplished 24 of 33 passes for 303 yards and three touchdowns with one interception. He additionally rushed six instances for 28 yards and two touchdowns.

San Francisco’s MVP could also be Christian McCaffrey, who doesn’t have an harm designation for the sport regardless of lacking observe on Tuesday (again). In 16 video games this season, he has carried 303 instances for 1,179 yards (3.9 common) and 10 touchdowns. He additionally leads the 49ers in receiving, with 96 receptions for 890 yards and 7 touchdowns. Within the win over the Bears, he carried 23 instances for 140 yards (6.1 common) and one landing, whereas catching 4 passes for 41 yards. See which staff to again at SportsLine.

The right way to make Seahawks vs. 49ers picks

SportsLine’s mannequin goes Over on the overall, projecting 51 mixed factors. It additionally says one aspect of the unfold hits in properly over 50% of simulations.  You may solely get the decide at SportsLine. 

So who wins 49ers vs. Seahawks, and which aspect of the unfold hits properly over 50% of the time? Go to SportsLine now to see which aspect of the Seahawks vs. 49ers unfold to leap on, all from the superior mannequin that completed up over $7,000 on its NFL picks since its inception, and discover out.

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